RORgt Mouse, Unlabeled, Clone: O28-835, BD

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Availablity: In stock
Catalog/Part Number: 15841719
Brand: BD Biosciences
Supplier: FISHER SCIENTIFIC
Supplier Location: LOUGHBOROUGH, UK
Inventory Weight: unavailable
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Catalog/Part Number:: 15841719

₦670,680.00

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Description

The O28-835 monoclonal antibody recognizes ROR-gamma ( RORγ) and its isoform, RORγt. RORγ(∽58 kDa calculated molecular weight) is a DNA-binding transcription factor that belongs to the ROR/RZR orphan nuclear receptor family. It is expressed in different tissues including skeletal muscle, kidney, liver and adipose tissues. RORγt ( ∽56 kDa calculated molecular weight ) is a RORγisoform that is expressed exclusively by lymphoid cells. It is expressed by various lymphoid cell types including CD4+CD8+ thymocytes, peripheral CD4+ Th17 and CD8+ Tc17 cells and lymphoid tissue inducer (Lti) cells. RORγt plays essential roles in thymopoiesis, T cell homeostasis, differentiation of effector T lymphocytes and the development of secondary lymphoid tissues including lymph nodes and Peyer’s patches.

Catalog/Part Number: 15841719 Category:

Technical Specifications

Antigen:  RORgt

Clone:  O28-835

Conjugate:   Unconjugated

Formulation:  Aqueous buffered solution containing ≤0.09% sodium azide.

Host Species:   Murine

Isotype:   IgG2b, κ

Regulatory Status:  RUO

Primary or Secondary:   Primary

Target Species:   Human, Murine

Applications:     Western Blot

Concentration:    0.5mg/mL

Description:   Rorc; Rorg; RORgamma; Rorγ; RORgt; RORgammat; RORγt; TOR; Thor; Nr1f3; ROR

Format:    Affinity Purified

Immunogen:   Human RORγt Recombinant Protein

Quantity:    0.1mg

Storage Requirements:   Store undiluted at 4°C

Monoclonal or Polyclonal:   Monoclonal

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