CD71 Rat anti-Mouse, FITC, Clone: C2, BD-2

Availablity: In stock

Catalog/Part Number: 15877108
Brand: BD Biosciences
Supplier: FISHER SCIENTIFIC
Supplier Location: LOUGHBOROUGH, UK
Inventory Weight: unavailable
Unit of Measurement:
Inventory Brochure: unavailable

Catalog/Part Number:: 15877108

₦834,210.00

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Description

The C2 monoclonal antibody specifically binds to CD71, the transferrin receptor. CD71 is a disulfide-linked homodimer of 95-kDa subunits. CD71 mediates one of the cellular mechanisms for iron uptake, and its expression is regulated according to the cell’s iron requirements. It is expressed at high levels on developing erythroid cells, and it is upregulated after mitogenic activation of B or T lymphocytes. The C2 monoclonal antibody selectivity inhibits some types of T- and B-cell activation by down-regulation of transferrin receptor expression, but it does not block binding of transferrin.

Catalog/Part Number: 15877108 Category:

Technical Specifications

Antigen: CD71

Clone:  C2

Conjugate: FITC

Formulation: Aqueous buffered solution containing ≤0.09% sodium azide.

Host Species: Rat

Isotype:  IgG1, κ

Regulatory Status:  RUO

Primary or Secondary:  Primary

Target Species:  Murine

Applications:  Flow Cytometry

Concentration:  0.5mg/mL

Description:  Transferrin Receptor; TR; TfR; TfR1; Tfrc; Trfr; Mtvr-1

Format:  Affinity Purified

Immunogen:  Mouse cell line

Quantity:   0.5mg

Storage Requirements:    Store undiluted at 4°C and protected from prolonged exposure to light. Do not freeze.

Monoclonal or Polyclonal:   Monoclonal

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