CD41a Mouse anti-Human, BUV395, Clone: HIP8, BD Optibuild™

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Availablity: In stock
Catalog/Part Number: 15866659
Brand: BD Biosciences
Supplier: FISHER SCIENTIFIC
Supplier Location: LOUGHBOROUGH, UK
Inventory Weight: unavailable
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Catalog/Part Number:: 15866659

₦1,494,540.00

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Description

The HIP8 monoclonal antibody specifically binds to the α -chain of CD41. CD41 is also known as Integrin α IIb or Platelet GPIIb. The calcium-dependent complex of CD41 and CD61 ( β 3 integrin or GPIIIa) is normally expressed on platelets and megakaryocytes. The CD41/CD61 complex is the receptor for fibrinogen, fibronectin and von Willebrand factor, and mediates platelet adhesion and aggregation. CD41 (clone HIP8) completely inhibits ADP-, epinephrine-, and collagen-induced platelet activation, and partially inhibits ristocetin- and thrombin-induced platelet activation. This antibody is useful in the morphological and physiological studies of platelets and megakaryocytes.

Catalog/Part Number: 15866659 Category:

Technical Specifications

Antigen:  CD41a

Clone:   HIP8

Conjugate:   Brilliant Ultraviolet 395

Formulation:  Aqueous buffered solution containing ≤0.09% sodium azide.

Host Species:   Murine

Isotype:     IgG1, κ

Quantity:   50μg

Storage Requirements:  Store undiluted at 4°C and protected from prolonged exposure to light. Do not freeze.

Monoclonal or Polyclonal:   Monoclonal

Applications:   Flow Cytometry

Concentration:   0.2mg/mL

Description:   ITGA2B; Integrin alpha-2b (αIIb); Platelet glycoprotein IIb (GPIIb)

Format:   Affinity Purified

Immunogen:   Purified platelet membrane glycoproteins

Purification Method:   The monoclonal antibody was purified from tissue culture supernatant or ascites by affinity chromatography.

Regulatory Status:    RUO

Primary or Secondary:  Primary

Target Species:   Human

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