CD123 Mouse anti-Human, Brilliant Violet 510, Clone: 9F5, BD

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Availablity: In stock
Catalog/Part Number: 15862489
Brand: BD Biosciences
Supplier: FISHER SCIENTIFIC
Supplier Location: LOUGHBOROUGH, UK
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Catalog/Part Number:: 15862489

₦759,690.00

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Description

The 9F5 monoclonal antibody specifically binds to CD123. CD123 is the 70 kDa IL-3 receptor α chain (IL-3Rα) that associates with the 120-140 kDa β subunit (CD131/Common β-chain/βc) to form the functional IL-3 receptor complex. The βc chain is also shared with distinct α chain subunits to form the functional heterodimeric receptors for interleukins IL-5 and GM-CSF. IL-3Rα is expressed on a subset of peripheral blood dendritic cells, myeloid precursors, basophils, mast cells, macrophages, and megakaryocytes. Reports indicate that IL-3Rα is also expressed on lymphocytes. The IL-3R plays an important role in hematopoietic progenitor cell growth and differentiation. This antibody does not block binding of IL-3 to the IL-3 receptor.

Catalog/Part Number: 15862489 Category:

Technical Specifications

Antigen:  CD123

Clone:   9F5

Description:   IL-3 Receptor α chain

Format:       Affinity Purified

Immunogen:    Human IL-3Rα Transfected Cell Line

Quantity:    50 Tests

Storage Requirements:   Store undiluted at 4°C and protected from prolonged exposure to light. Do not freeze.

Monoclonal or Polyclonal:   Monoclonal

Applications:   Flow Cytometry

Conjugate:    Brilliant Violet 510

Formulation:    Aqueous buffered solution containing BSA and ≤0.09% sodium azide.

Host Species:    Murine

Isotype:   IgG1, κ

Regulatory Status:    RUO

Primary or Secondary:   Primary

Target Species:   Human

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